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Measured physicochemical water parameters including conducti
2022-05-09
Measured physicochemical water parameters including conductivity, suspended solids and nutrient load along the studied sites (Table 1) were high compared to levels usually found in undisturbed rivers within Europe (Chapman and Kimstach, 1996). In particular conductivity, suspended solids and phospha
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Not all metals are susceptible of being accumulated by
2022-05-09
Not all metals are susceptible of being accumulated by insects. Tissue concentrations of essential metals like Cu and Zn are regulated in many insects and hence cannot be used to biomonitor metal pollution (Hare, 1992). A similar behaviour could explain the observed stability of Zn and Cu relative t
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Evans Blue tetrasodium salt A few of the islet
2022-05-07
A few of the islet-specific proteins identified in the present study have previously been described in various contexts of pancreatic islets, i.e. PTPRN, SCG5, SCGN, SNAP25 and SNED1, validating the search algorithm applied and supporting the notion that also the novel proteins identified are indeed
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Although it is currently unknown
2022-05-07
Although it is currently unknown why the longer splice variant found in the human has not been found in any other species, similar results have been reported for other receptors, including the nice to you receptor splice variant ERbeta2 identified in human and primate, but not other species (Sieren
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br GPR a G protein coupled receptor
2022-05-07
GPR35, a G protein-coupled receptor (GPCR), was discovered and classified as an orphan GPCR in 1998 and deorphanized in 2006 by the discovery of kynurenic Amsacrine hydrochloride receptor as the endogenous agonist. Since its discovery, limited references on the GPR35 receptor have appeared, due i
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Terbutaline Sulfate It was reported that GPR
2022-05-07
It was reported that GPR120 is expressed on macrophages in adipose tissue (Oh et al., 2010). Whether GPR120-positive Terbutaline Sulfate in human and rat pancreas belongs to macrophages was studied. CD68 is a transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophag
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Introduction GPR is a class A
2022-05-07
Introduction GPR119 is a class A type of G Protein coupled receptor, which is expressed primarily in pancreatic β-cells and the K and L dorsomorphin of the gastrointestinal tract [1], [2], [3]. Activation of GPR119 promotes secretion of incretins such as glucagon-like peptide-1 (GLP-1) in the inte
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The biological activity at GPR a of each of
2022-05-07
The biological activity at GPR109a of each of the 4-functionalized-5-alkyl-pyrazole-3-carboxylic acids (–) was measured using a cAMP whole cell Dynamic2 Homogenous Time-Resolved Fluorescence (HTRF) assay (). Twelve compounds were found to exhibit an EC below 1μM, and of these seven exhibited EC valu
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br Introduction Few decades after of HIV AIDS
2022-05-07
Introduction Few decades after of HIV/AIDS diagnosis, it has been still a health problem and impact will continue in the next decades. In 2015, HIV/AIDS was the 12th cause of death in the world and it's estimated that 1.2 million people was died of HIV/AIDS this year. In the global epidemiologica
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br Materials and methods br Results and discussion br
2022-05-07
Materials and methods Results and discussion Conclusions In summary, the Au@SiO2 based lateral flow sandwich immunoassay for fast detection of EBN-specific glycoprotein has been firstly established by using nanocomposites as signaling-labels and synthesized EBN-specific leukotriene b4 recep
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GlyRs are members of the superfamily
2022-05-07
GlyRs are members of the superfamily of Cys-loop receptors (CLRs) [3]. They form postsynaptic pentameric receptor complexes of α1 and β subunits anchored via the scaffolding protein gephyrin [4]. GlyRs are composed of several domains with the large N-terminal extracellular domain (ECD) important for
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The CO chemosensitivity of the LH PFA has been shown
2022-05-07
The CO2 chemosensitivity of the LH/PFA has been shown to be dependent on sleep-wake states (B.S. Deng et al., 2007; Dias et al., 2010, 2009; Li et al., 2013). In this context, it was demonstrated that focal acidification of the LH/PFA, by microdialysis of acidic artificial cerebrospinal fluid (aCSF)
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Our study has some limitations that should
2022-05-07
Our study has some limitations that should be considered when the results are interpreted. First, we did not measure the protein levels of Bax and Bcl2, due to time and budget limitations. Although simultaneous measurements of both mRNA and protein levels are complementary for a better understanding
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When we compared the effects in FST
2022-05-07
When we compared the effects in FST induced by GAL and GAL(1–15), we observed that the increase in the immobility induced by GAL(1–15) was significantly higher than the one induced by GAL (Millon et al., 2015). Moreover, in climbing behaviour, GAL(1–15) also induced a stronger decrease in climbing r
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We have previously designed an azobenzene based molecule Raz
2022-05-07
We have previously designed an azobenzene-based molecule, Razo, which could switch the conformations of G-quadruplex structures by photoregulation. 12, 13, 14, 15 However, it lacks selectivity to different G-quadruplexes. Therefore, we want to find a way to modify this molecule so that it could be u
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